Translating Bio-Repositories into New Clinical Insights

MCT Research Forum – February, 25th 2019 at 12.00, Cheyne LT

Prof. Paul McNally – “Biorepositories in Childhood Cystic Fibrosis: A Journey of Discovery”
Paul graduated from the UCD School of Medicine in 1998. He completed his paediatric medical training in Ireland, and subsequently completed a 2-year MD in Cystic Fibrosis (CF) lung disease in the Royal College of Surgeons in Ireland. Paul undertook pulmonology fellowship training in the Children’s Hospital of Philadelphia from 2007 to 2009. He was appointed as a consultant in Paediatric Respiratory Medicine at Our Lady’s Children’s Hospital (OLCHC) in 2009. In August 2015, Paul was appointed as Associate Professor of Paediatrics at RCSI. Paul is director of the CF centre in OLCHC and leads the CF research group at NCRC. Paul is clinical lead for Paediatric Respiratory Medicine in the Dublin Paediatric Hospitals. He is a board member of the CF Registry of Ireland and the National Children’s Research Centre. Paul is a member of the working group of the National Clinical Programme for Cystic Fibrosis and is a member of the advisory board for the National Clinical Programme for Paediatrics. Paul has recently been appointed as the director of research and innovation for Children’s Health Ireland (Dublin’s three children’s Hospitals). Paul’s main research interest is early CF lung disease, in particular around the question of why some children have more severe lung disease, and how we can detect these children earlier and modify their treatment.

Dr. Michelle Lavin – “The future of data repositories and e-Health in Irish clinical research”
Dr. Michelle Lavin is a Consultant Haematologist and the Clinical Lead for the Irish Personalised Approach to the Treatment of Haemophilia (iPATH) study, based in the Irish Centre for Vascular Biology, RCSI. She completed her PhD in Trinity College Dublin, focused on the pathophysiology and clinical impact of Low Von Willebrand Factor (VWF) levels. Her research is centred on inherited bleeding disorders; developing insights into phenotypic variability and working to improve clinical outcomes. She serves a Co-Chair on the International Society on Thrombosis and Haemostasis (ISTH) VWF Scientific Subcommittee and a clinical advisor to the World Federation of Haemophilia.

Chair: Soracha Ward
A light lunch will be served after the talks

Sponsored by Biosciences

Fantastic achievements of Lisa Dwane and Lauren Fagan

Dr. Lisa Dwane post doc with Prof. Darran O’Connor’s group, is Irish Cancer Society’s PhD Scholar of the Year 2019. She presenting her research in layman’s terms to compete for the prize at the ICS Research Awards held on Friday 15th February, at the House of Lords, Bank of Ireland College Green, Dublin 2.

Lisa also received the EACR Young Scientist Award, in the Junior category, for her research in cancer research. This Young Scientist award is granted to the two applicants with the highest scoring abstracts. This year, both recipients are RCSI researchers; the second applicant Dr. Sara Charmsaz, Dept. of Surgery, received the Senior award. Awards will be presented at the IACR Annual Conference, on Friday 22nd February, in Belfast.

Lauren Fagan (co-supervised by Dr. Oran Kennedy and Dr. Annie Curtis) was awarded Best Musculoskeletal Research Oral Presentation – Early Researcher Category for her early stage work on the chondrocyte clock and post-traumatic osteoarthritis at the Royal Academy of Medicine in Ireland Section of Bioengineering 25th Annual Conference (BinI 2019), UL, 18th – 19thJanuary 2019.

Hot Chocolate Morning for International Childhood Cancer Day

Dr Olga Piskareva’s team ran the Hot Chocolate Morning on February, 15th. Every year that day, we celebrate the International Childhood Cancer Day (ICCD) to raise awareness of childhood cancer, its consequences for children and their parents and make it as a priority for Governments and research.

Olga’s research is focused on neuroblastoma biology. This is a solid tumour of undeveloped nerves. Some forms of neuroblastoma spread quickly and become very aggressive and challenging to treat. Her team is searching for the weaknesses in cancer spread that can be targeted with drugs.

Ciara, John, Tom, Nele and Olga (l-r)

Olga teamed up with Amorino to offer authentic traditional Italian hot chocolate to raise funds for childhood cancer research charities – Children’s Medical Research Foundation/National Children’s Research Centre and the Conor Foley Neuroblastoma Cancer Research Foundation.  Research advances our knowledge and helps to develop new treatments.

A guessing game was a part of the event. Everyone had a chance to guess how many marshmallows fitted in the cell culture flask T75. The guesses ranged from as low as 95 to as high as 500. Fortunately, one of the participants gave an absolutely correct answer. Micheal Flood put on 173 and won. Her fantastic ability to guess is incredible! Congratulations!!! Well done to all!

Olga’s team raised 698.91 Euros for childhood cancer research! They thank everyone who came along and supported the Hot Chocolate Morning & the International Childhood Cancer Day 2019! They thank Amorino for delicious chocolate & tasty bites contributors!

And the winners are:

1st place – Micheal Flood (173)
2nd place – Rebecca Watkin (175)
3d place – Lisa Dwane (180)
4th place – Billy Cahill (165)
5th place – Martin Kenny (185)
6th place Brona Murphy (160)

 

Ciara, Nele, John, Tom and Olga

Genomes and Genome Modification

MCT Research Forum – Monday 11th February 2019 at 3.00pm Houston Lecture Theatre

Chair: Martin Kenny

Speakers:

Prof. Gianpiero Cavalleri

Genome-wide mega-analysis in the epilepsies”

Dr. Cormac McDonnell

“CRISPR strategies for protein engineering”

Dr. Elspeth Ward

“Editing the genome using CRISPR/Cas9”

 Tea/Coffee and Cookies at 2.45pm sponsored by